Review



inverted microscope nikon ti s whole cell macroscopic current recordings  (Nikon)


Bioz Verified Symbol Nikon is a verified supplier  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 99
      Buy from Supplier

    Structured Review

    Nikon inverted microscope nikon ti s whole cell macroscopic current recordings
    Testing inhibitory properties of SIL14 with patch-clamp. A Chemical structure of SIL14. B Representative current trace of pannexin-1 activity with 300 µM SIL14 <t>application.</t> <t>Whole-cell</t> recordings were obtained on CHO cells transiently transfected with mPanx1 under [90; −90] mV ramps. C Current–voltage characteristic of pannexin-1 conductance before and after SIL14 application. D Dose dependency of SIL14 effect on pannexin-1 measured at + 80 mV reveals IC 50 = 12.96 µM according to nonlinear regression analysis
    Inverted Microscope Nikon Ti S Whole Cell Macroscopic Current Recordings, supplied by Nikon, used in various techniques. Bioz Stars score: 99/100, based on 14251 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/nikon+ti+s+inverted+microscope/pmc12819920-54-24-26?v=Nikon
    Average 99 stars, based on 14251 article reviews
    inverted microscope nikon ti s whole cell macroscopic current recordings - by Bioz Stars, 2026-08
    99/100 stars

    Images

    1) Product Images from "Abnormal purinergic signaling contributes to development of renal cysts in autosomal dominant polycystic kidney disease"

    Article Title: Abnormal purinergic signaling contributes to development of renal cysts in autosomal dominant polycystic kidney disease

    Journal: Purinergic Signalling

    doi: 10.1007/s11302-025-10127-1

    Testing inhibitory properties of SIL14 with patch-clamp. A Chemical structure of SIL14. B Representative current trace of pannexin-1 activity with 300 µM SIL14 application. Whole-cell recordings were obtained on CHO cells transiently transfected with mPanx1 under [90; −90] mV ramps. C Current–voltage characteristic of pannexin-1 conductance before and after SIL14 application. D Dose dependency of SIL14 effect on pannexin-1 measured at + 80 mV reveals IC 50 = 12.96 µM according to nonlinear regression analysis
    Figure Legend Snippet: Testing inhibitory properties of SIL14 with patch-clamp. A Chemical structure of SIL14. B Representative current trace of pannexin-1 activity with 300 µM SIL14 application. Whole-cell recordings were obtained on CHO cells transiently transfected with mPanx1 under [90; −90] mV ramps. C Current–voltage characteristic of pannexin-1 conductance before and after SIL14 application. D Dose dependency of SIL14 effect on pannexin-1 measured at + 80 mV reveals IC 50 = 12.96 µM according to nonlinear regression analysis

    Techniques Used: Patch Clamp, Activity Assay, Transfection



    Similar Products

    inverted microscope nikon ti s whole cell macroscopic current recordings  (Nikon)
    99
    Nikon inverted microscope nikon ti s whole cell macroscopic current recordings
    Testing inhibitory properties of SIL14 with patch-clamp. A Chemical structure of SIL14. B Representative current trace of pannexin-1 activity with 300 µM SIL14 <t>application.</t> <t>Whole-cell</t> recordings were obtained on CHO cells transiently transfected with mPanx1 under [90; −90] mV ramps. C Current–voltage characteristic of pannexin-1 conductance before and after SIL14 application. D Dose dependency of SIL14 effect on pannexin-1 measured at + 80 mV reveals IC 50 = 12.96 µM according to nonlinear regression analysis
    Inverted Microscope Nikon Ti S Whole Cell Macroscopic Current Recordings, supplied by Nikon, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/nikon+ti+s+inverted+microscope/pmc12819920-54-24-26?v=Nikon
    Average 99 stars, based on 1 article reviews
    inverted microscope nikon ti s whole cell macroscopic current recordings - by Bioz Stars, 2026-08
    99/100 stars
    		  Buy from Supplier
    nikon ti s inverted microscope  (Nikon)
    99
    Nikon nikon ti s inverted microscope
    Testing inhibitory properties of SIL14 with patch-clamp. A Chemical structure of SIL14. B Representative current trace of pannexin-1 activity with 300 µM SIL14 <t>application.</t> <t>Whole-cell</t> recordings were obtained on CHO cells transiently transfected with mPanx1 under [90; −90] mV ramps. C Current–voltage characteristic of pannexin-1 conductance before and after SIL14 application. D Dose dependency of SIL14 effect on pannexin-1 measured at + 80 mV reveals IC 50 = 12.96 µM according to nonlinear regression analysis
    Nikon Ti S Inverted Microscope, supplied by Nikon, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/nikon+ti+s+inverted+microscope/10__3390_slash_cells15010055-81-45-45?v=Nikon
    Average 99 stars, based on 1 article reviews
    nikon ti s inverted microscope - by Bioz Stars, 2026-08
    99/100 stars
    		  Buy from Supplier
    inverted microscope nikon ti-s  (Nikon)
    90
    Nikon inverted microscope nikon ti-s
    Testing inhibitory properties of SIL14 with patch-clamp. A Chemical structure of SIL14. B Representative current trace of pannexin-1 activity with 300 µM SIL14 <t>application.</t> <t>Whole-cell</t> recordings were obtained on CHO cells transiently transfected with mPanx1 under [90; −90] mV ramps. C Current–voltage characteristic of pannexin-1 conductance before and after SIL14 application. D Dose dependency of SIL14 effect on pannexin-1 measured at + 80 mV reveals IC 50 = 12.96 µM according to nonlinear regression analysis
    Inverted Microscope Nikon Ti S, supplied by Nikon, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/nikon+ti+s+inverted+microscope/pmc10092759__ijbsv19p1681s1-14-11-11?v=Nikon
    Average 90 stars, based on 1 article reviews
    inverted microscope nikon ti-s - by Bioz Stars, 2026-08
    90/100 stars
    		  Buy from Supplier
    inverted microscope nikon eclipse ti-s  (Nikon)
    90
    Nikon inverted microscope nikon eclipse ti-s
    Testing inhibitory properties of SIL14 with patch-clamp. A Chemical structure of SIL14. B Representative current trace of pannexin-1 activity with 300 µM SIL14 <t>application.</t> <t>Whole-cell</t> recordings were obtained on CHO cells transiently transfected with mPanx1 under [90; −90] mV ramps. C Current–voltage characteristic of pannexin-1 conductance before and after SIL14 application. D Dose dependency of SIL14 effect on pannexin-1 measured at + 80 mV reveals IC 50 = 12.96 µM according to nonlinear regression analysis
    Inverted Microscope Nikon Eclipse Ti S, supplied by Nikon, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/nikon+ti+s+inverted+microscope/pmc12214791-73-1-2?v=Nikon
    Average 90 stars, based on 1 article reviews
    inverted microscope nikon eclipse ti-s - by Bioz Stars, 2026-08
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    Testing inhibitory properties of SIL14 with patch-clamp. A Chemical structure of SIL14. B Representative current trace of pannexin-1 activity with 300 µM SIL14 application. Whole-cell recordings were obtained on CHO cells transiently transfected with mPanx1 under [90; −90] mV ramps. C Current–voltage characteristic of pannexin-1 conductance before and after SIL14 application. D Dose dependency of SIL14 effect on pannexin-1 measured at + 80 mV reveals IC 50 = 12.96 µM according to nonlinear regression analysis

    Journal: Purinergic Signalling

    Article Title: Abnormal purinergic signaling contributes to development of renal cysts in autosomal dominant polycystic kidney disease

    doi: 10.1007/s11302-025-10127-1

    Figure Lengend Snippet: Testing inhibitory properties of SIL14 with patch-clamp. A Chemical structure of SIL14. B Representative current trace of pannexin-1 activity with 300 µM SIL14 application. Whole-cell recordings were obtained on CHO cells transiently transfected with mPanx1 under [90; −90] mV ramps. C Current–voltage characteristic of pannexin-1 conductance before and after SIL14 application. D Dose dependency of SIL14 effect on pannexin-1 measured at + 80 mV reveals IC 50 = 12.96 µM according to nonlinear regression analysis

    Article Snippet: For each patch-clamp experiment, a glass chip with cells was transferred into the chamber with a constant flow of bath solution, placed under the inverted microscope Nikon Ti-S. Whole-cell macroscopic current recordings of pannexin-1 were made under voltage-clamp conditions with ramp protocol (90- > −90 mV).

    Techniques: Patch Clamp, Activity Assay, Transfection